Analgesia effect of Canelim Capsules on mice with heat-induced pain

Yuan B. Xiang et al., Xian Medical University

Result:

Group	cases	Dosage	Pain threshold (second)
	(n)	(mg/kg)	before admin	30' after admin	60' after admin
Water control	10	---	18.90 ¡À 3.68	19.18 ¡À 3.68	19.68 ¡À 4.15
Aspirin	10	100	18.40 ¡À 3.24	32.80 ¡À 2.82**	44.00 ¡À 3.97**
Canelim	10	100	17.60 ¡À 4.81	21.90 ¡À 3.48	27.40 ¡À 2.32**
	10	200	16.90 ¡À 3.48	29.10 ¡À 2.18**	38.20 ¡À 2.44**
	10	400	17.80 ¡À 2.94	35.30 ¡À 3.16**	48.00 ¡À 4.20**

compared with water control, * means p<0.05, ** means p<0.01

Discuss:

Compared with water control, the pain shreshold is significantly (p<0.01) increased after the administration of Canelim capsules. And this effect amplifies while dosage increases, according to Tr test.

Conclusion:

Canelim Capsules can greatly increase pain threshold of mice with heat-induced pain.