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Analgesia effect of Canelim Capsules on mice with heat-induced pain

Yuan B. Xiang et al., Xian Medical University

Result:

Group
cases
Dosage
Pain threshold (second)
(n)
(mg/kg)
before admin
30' after admin
60' after admin
Water control
10
---
18.90 3.68
19.18 3.68
19.68 4.15
Aspirin
10
100
18.40 3.24
32.80 2.82**
44.00 3.97**
Canelim
10
100
17.60 4.81
21.90 3.48
27.40 2.32**
10
200
16.90 3.48
29.10 2.18**
38.20 2.44**
10
400
17.80 2.94
35.30 3.16**
48.00 4.20**

compared with water control, * means p<0.05, ** means p<0.01

Discuss:

Compared with water control, the pain shreshold is significantly (p<0.01) increased after the administration of Canelim capsules. And this effect amplifies while dosage increases, according to Tr test.

Conclusion:

Canelim Capsules can greatly increase pain threshold of mice with heat-induced pain.

 

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